O'Really?

May 4, 2010

Ian Wilmut on the World after Dolly the Sheep

Bicolor sheep by Tambako the Jaguar, on FlickrAs part of the Gates Distinguished Lecture Series, Ian Wilmut will be giving a public lecture today in Cambridge titled Cloning, Stem Cells and Regenerative Medicine: The World After Dolly. More details below from talks.cam.ac.uk:

“Ian Wilmut soared to international prominence when Dolly, a baby lamb created from the cells of an adult sheep [1,2], was revealed to the world. Dolly was the first genetic replica of a living creature created from cells from an adult animal. The accomplishment sparked amazement and controversy as scientists, philosophers, ethicists and religious leaders perceived the potential to extend such work to humans.”

All are encouraged to attend, lecture starts at 6pm today the Cambridge Union Society see press release from the University. [Update: Note last minute change from previously advertised venue at Emmanuel College, Cambridge. See also the accompanying podcast page].
Audio of talk available

References

  1. Campbell, K., McWhir, J., Ritchie, W., & Wilmut, I. (1996). Sheep cloned by nuclear transfer from a cultured cell line Nature, 380 (6569), 64-66 DOI: 10.1038/380064a0
  2. Wilmut, I., Schnieke, A., McWhir, J., Kind, A., & Campbell, K. (1997). Viable offspring derived from fetal and adult mammalian cells Nature, 385 (6619), 810-813 DOI: 10.1038/385810a0

March 17, 2010

Hunkin’s Hypothesis: Technology Is What Makes Us Human

Tim Hunkin: Technology is What Makes Us HumanCartoonist and engineer Tim Hunkin is probably best known for his exhibits at the Science Museum in London and his Under The Pier Show “a mad arcade of home-made slot machines & simulator rides on Southwold Pier, Suffolk”.  His website is a treasure trove of weird and wonderful things.

Tim has an interesting proposition, let’s call it Hunkin’s Hypothesis [1], that technology is what makes us human:

“Technology isn’t just something outside ourselves, it’s an innate part of human nature, like sex, sleeping or eating, and that its been a major driving force in evolution. Tool using, along with language and bipedalism, is essentially what makes us human. The complicated theories used to explain why we first stood up are largely unnecessary. Our hands simply became too useful for holding tools to waste them on walking.”

He bases this idea, on a paper published by Frances Evans [2] about the creative engineering mind. This idea has at least two important implications:

  1. Engineering is a creative and intellectual process that humans do instinctively, not an obsolete and dying skill practiced by dinosaurs
  2. Engineering is an essential part of education, that needs to be taught more in schools and universities. Tim encourages his grand-children to use spot-welders, glue-guns and soldering irons at every opportunity! In UK schools health and safety regulations, plus the fear of being sued often make this tricky.

I’m not sure what to make of Hunkin’s Hypothesis yet, but it’s an intriguing idea that deserves investigation.

References

  1. Tim Hunkin (2006). Technology is what makes us human. timhunkin.com
  2. Frances Evans (1998). Two legs, thing using and talking: The origins of the creative engineering mind AI & Society, 12 (3), 185-213 DOI: 10.1007/BF01206195
  3. Tim Hunkin – The Seaside Inventor, Southwold Pier, Suffolk

[Picture of Tim Hunkin taken from his talk at Cambridge Science Festival, 2010.]

May 15, 2009

Y.M.C.A. – Just a little bit of G.T.C.A.

OK, look I know that by posting the latest viral marketing video from Bio-Rad Laboratories, Inc. I’m just a pawn (or vector) in their advertising game. This particular video has been around for a couple of months now but it is probably poor internet hygiene to spread these pandemic viral videos. I should just catch it, kill it and bin it. However, I can’t resist this one any longer because, like the last one, it is pretty kitsch, pretty funny and in a strange way, it might just increase the public awareness of Science. Maybe.

And it’s Friday today too, so to the tune of Y.M.C.A. by the Village People, you are now infected with just a little bit of (altogether now…) G.T.C.A.!

The lyrics go a little something like this: (more…)

March 16, 2009

March 12, 2009

Defrosting the Digital Seminar

The Lecture by James M ThorneCasey Bergman suggested it, Jean-Marc Schwartz organised it, so now I’m going to do it: a seminar on our Defrosting the Digital Library paper as part of the Bioinformatics and Functional Genomics seminar series. Here is the abstract of the talk:

After centuries with little change, scientific libraries have recently experienced massive upheaval. From being almost entirely paper-based, most libraries are now almost completely digital. This information revolution has all happened in less than 20 years and has created many novel opportunities and threats for scientists, publishers and libraries.

Today, we are struggling with an embarrassing wealth of digital knowledge on the Web. Most scientists access this knowledge through some kind of digital library, however these places can be cold, impersonal, isolated, and inaccessible places. Many libraries are still clinging to obsolete models of identity, attribution, contribution, citation and publication.

Based on a review published in PLoS Computational Biology, http://pubmed.gov/18974831 this talk will discuss the current chilly state of digital libraries for biologists, chemists and informaticians, including PubMed and Google Scholar. We highlight problems and solutions to the coupling and decoupling of publication data and metadata, with a tool called http://www.citeulike.org. This software tool exploits the Web to make digital libraries “warmer”: more personal, sociable, integrated, and accessible places.

Finally issues that will help or hinder the continued warming of libraries in the future, particularly the accurate identity of authors and their publications, are briefly introduced. These are discussed in the context of the BBSRC funded REFINE project, at the National Centre for Text Mining (NaCTeM.ac.uk), which is linking biochemical pathway data with evidence for pathways from the PubMed database.

Date: Monday 16th March 2008, Time: 12.00 midday, Location: Michael Smith Building, Main lecture theatre, Faculty of Life Sciences, University of Manchester (number 71 on google map of the Manchester campus). Please come along if you are interested…

[CC licensed picture above, “The Lecture” at Speakers Corner by James M Thorne]

February 25, 2009

A Fistful Of Papers: Journal Club for Gunslingers

Filed under: biotech — Duncan Hull @ 4:30 pm
Tags: , , ,

Clint Eastwood by DunechaserA Fistful of Papers is a Journal Club with a simple recipe

  1. We pick interesting papers
  2. We read them
  3. We periodically meet to discuss said papers in the pub local saloon

It’s all good fun, if you’d like to join us, details of the next gathering on Friday 27th February, can be found over at fistful.wordpress.com (Journal Club for Gunslingers).

[Clint Eastwood picture by Lego Man Andrew Becraft a.k.a. Dunechaser]

September 29, 2008

BBSRC UK Roadshow, Autumn 2008

bend in the roadThe Biotechnology and Biological Sciences Research Council (BBSRC) is on the road this autumn in London, Manchester, Bristol, Glasgow and Cambridge. Potential applicants, grant holders and any other interested parties are strongly urged to attend and learn about BBSRC’s plans for the future including new procedures and new Committee structures. The road shows will also provide an opportunity to meet the new members of the BBSRC Senior Management team.

From an original email sent by Alf Game, Deputy Director of Science and Technology Group. See BBSRC Roadshows.

The BBSRC has revised its future strategic priorities and the way in which they will be delivered through responsive mode peer review and is holding a series of road shows “Enabling the Delivery of Excellence with Impact” at various locations across the UK. (more…)

July 25, 2008

How to spend a £400 million Science budget

A thought experiment with lots of money

The Queens Ahead by canonsnapperThe Biotechnology and Biological Sciences Research Council (BBSRC) is the United Kingdom’s funding agency for academic research and training in the non-clinical life sciences. It supports a total of around 1600 scientists and 2000 research students in universities and institutes in the UK. The head of our laboratory, Douglas Kell, has recently been appointed Chief Executive of the BBSRC [1]. Congratulations Doug, we wish you the very best in your new job. Now, according to bbsrc.ac.uk, their annual budget is a cool £400 million (just short of $800 million or €500 million). This has left me wondering, how would you spend a £400 million Science budget for the life sciences? For the purposes of this article, imagine it was you that had been put in charge of said budget, and Prime Minister Gordon Brown (texture like sun) had given you, yes YOU, a big bag of cash to distribute as you see fit. A mouth-watering prospect, I think you’ll agree. Here, is my personal opinion of how, in my dreams, I would spend the money. (more…)

April 14, 2008

Ensemblog: The Ensembl Weblog

Filed under: biotech — Duncan Hull @ 11:51 am
Tags: , , , , , ,

Pongo pygmaeus abeliiThe Ensembl Weblog provides news, views and announcements about the Ensembl Genome Browser. The blog has been going for a few years now, but I have only just become aware of it thanks to a recent Ensembl Genome Browser Tutorial by Bert Overduin. Catching up on posts from Ensemblians this year, Ewan Birney wrote a piece about The Gene Love-in last week and Paul Flicek briefly described the 1000 Genomes project back in January. The Ensembl Weblog is fairly low traffic, so if you don’t already read it, it’s worth considering subscribing to the feed.

And it’s good to see more scientists using blogs to communicate. Long may this trend continue!

(more…)

March 28, 2008

How much does a Genome cost?

Dollars by PfalaBack in 2003 The Human Genome cost approximately $500 million, years of work and huge international effort to produce. How much does a genome cost now, and what might it cost in the future? (more…)

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